What is the electronic Neurostatus-EDSS
(Neurostatus e-EDSS)?

The Neurostatus-eEDSS provides a digital capture and documentation as well as an algorithm-based consistency check and automated real-time feedback on the Neurostatus-EDSS assessments data. Specifically, the algorithm detects inconsistencies in the scores made by raters, i.e. combinations of scores that do not match the rules described in the Neurostatus-EDSS Definitions. Assessments labelled as inconsistent can then be reviewed by the team of Neurostatus-EDSS experts who support the rater in their resolution.

What are the benefits of the Neurostatus-eEDSS in clinical or academic trials?

  • increasing data consistency
  • providing a complete digital data capture with no missing values and direct analysis
  • integrating into an expert-based review system to clarify individual inconsistencies in assessments

1. eCOA

For research trials studies wanting to capture EDSS assessments digitally, the eEDSS is currently being provided by three external electronic clinical outcome assessment (eCOA) companies under non-exclusive licenses.

2. Retrospective analysis

Depending on the studies’ requirements and complexities, the eEDSS can also be provided through the Neurostatus-UHB in-house digital solutions.  The inhouse Neurostatus-eEDSS service provides a retrospective consistency check and automatic calculation of the EDDS step based on the Functional System Scores (FSS) and the Ambulation Score (AS) (synopsis check only). This inhouse aims to support smaller or academic studies not able to use the full eCOA solution, who still wish to reduce variability and calculation errors and to improve the quality of their Neurostatus-EDSS study data.